From the following statements regarding nucleophilic displacement, which is CORRECT?
A. Ethers are more reactive than esters.
B. Amines are more reactive than amides.
C. Saturated carbons are more reactive than acyl carbon.
D. Acid chlorides are more reactive than alkyl chloride.
In chemical reactivity and nucleophilic displacement, nucleophilic substitution occurs more readily at an acyl carbon (ie., -RCO) than at a saturated carbon. Hence, a compound having a carbonyl group would be more prone to undergo nucleophilic substitution, for example, amides would be more prone than amines, acid chlorides more than alkyl chlorides, and esters more than ethers.