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A number is divisible by 3 if the sum of its digits is divisible by 3. In choice B, the sum of the digits of 4308 is 4 + 3 + 0 + 8 = 15, which is divisible by 3. In choice D, the sum of the digits is 23,451 is 2 + 3 +4 + 5 + 1 = 15, so choice D is also divisible by three. A number is divisible by 2 only if its last digit is even. Since the last digit of 4308 is even but the last digit of 23,451 is odd, the correct choice must be option B.